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Kumar Singh, Santosh
- Antibiotic Resistance Pattern and Clonal Relationship of Enterobacter Spp Isolates from Different Clinical Samples in Odisha, India
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Authors
Affiliations
1 Department of Microbiology, Institute of Medical Sciences, Kalinga Nagar, Bhubaneswar, Odisha,, IN
2 School of Health and Allied Science, Arka Jain University, Jamshedpur-832108, Jharkhand, IN
1 Department of Microbiology, Institute of Medical Sciences, Kalinga Nagar, Bhubaneswar, Odisha,, IN
2 School of Health and Allied Science, Arka Jain University, Jamshedpur-832108, Jharkhand, IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 1 (2022), Pagination: 288-292Abstract
Bacteria with increase antibiotics resistant caused serious health treat worldwide. Regular surveillance of resistance spectra and clonal relationship of infectious bacteria are important for appropriate use of antibiotics. In this study, we investigated the antibiotic resistant pattern and clonal relationship of Enterobacter spp isolated from different clinical samples of a tertiary care hospital of Odisha, India. The results of this study indicated the presence of multidrug resistant Enterobacter spp with multiple β-lactamases production. The phylogenetic tree showed three unique clusters of ERIC within the nineteen Enterobacter spp. isolates.Keywords
Enterobacter spp, Multidrug resistant, β-lactamase, ERIC-PCR, Multiple Antibiotic Resistant indexReferences
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- Isolation and Identification of Antibacterial Compound from Actinomycetes Isolated from Mangrove Soil
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Authors
Riya Jalan
1,
Biswaranjan Pradhan
2,
Santosh Kumar Singh
3,
Anuradha Das
4,
Rajib Lochan Barik
5,
Jyotisikha Meher
1,
Rashmi Ranjan Mishra
1,
Debasmita Dubey
6,
Bikash Chandra Behera
1
Affiliations
1 Department of Biotechnology, MITS School of Biotechnology, Odisha - 751024, IN
2 S.K. Dash Centre of Excellence of Biosciences and Engineering and Technology, Indian Institute of Technology, Bhubaneswar - 752050, IN
3 Department of Biotechnology, School of Health and Allied Sciences, ARKA JAIN University, Jamshedpur – 831001, IN
4 School of Chemical Sciences, National Institute of Science Education and Research, Bhubaneswar - 752050, IN
5 District Public Health Laboratory, District Head Quarters Hospital, Baripada - 757001, IN
6 Department of Biotechnology and Bioinformatics, Sambalpur University Jyotivihar - 768019, IN
1 Department of Biotechnology, MITS School of Biotechnology, Odisha - 751024, IN
2 S.K. Dash Centre of Excellence of Biosciences and Engineering and Technology, Indian Institute of Technology, Bhubaneswar - 752050, IN
3 Department of Biotechnology, School of Health and Allied Sciences, ARKA JAIN University, Jamshedpur – 831001, IN
4 School of Chemical Sciences, National Institute of Science Education and Research, Bhubaneswar - 752050, IN
5 District Public Health Laboratory, District Head Quarters Hospital, Baripada - 757001, IN
6 Department of Biotechnology and Bioinformatics, Sambalpur University Jyotivihar - 768019, IN
Source
Research Journal of Pharmacy and Technology, Vol 15, No 4 (2022), Pagination: 1461-1466Abstract
Nine actinobacteria were isolated from the mangrove soil of Bhitarkanika and screened for their bioactive metabolites and antimicrobial property. Out of the nine actinobacterial isolates, the bacterial isolateBAB-7 showed positive activity towards most of the enzymesscreened,i.e., Cellulase, phosphate solubilization, L-asparaginase, protease, and amylase. The actinobacterial isolate BAB-7 also exhibited antimicrobial activity against K. pneumoniae, V. alginolyticus, V. parahaemolyticus, P. aeruginosa,E. coli, S. typhimurium, and S. salivarius. Based on biochemical characterization, the actinobacterial isolate BAB-7 was identified asSteptomcessp.The secondary metabolites produced by the bacterial strain were analyzed through GC-mass spectroscopy and found to besimilar to the peaks of2-cyclohex-3-en-1-yl-2-oxoacetic acid derivative (ketomycin).Keywords
Antibiotics, bioactive metabolites, actinobacteria, mangrove.References
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